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目的探讨孕中期胎儿体重与孕妇血糖的关系。方法选取该院2015年1月—2016年12月就诊的61例妊娠中期胎儿体重大于相应孕周作为观察组,同时随机选取同期的40例妊娠中期胎儿体重符合相应孕周作为对照组,彩超检测胎儿体重,同时检测孕妇空腹血糖(FDG)、餐后2h血糖,总胆固醇、甘油三脂、高密度脂蛋白、低密度脂蛋白的水平。结果观察组胎儿体重(1 010.93±57.56)g,对照组(859.18±58.27)g,二组差异具有统计学意义(P<0.05);观察组孕妇孕期体重增长(18.87±2.87)g,对照组增长(13.20±4.48)g,二组差异具有统计学意义(P<0.05);观察组孕妇空腹血糖(FDG)(4.92±0.58)mmol/L,对照组(4.29±0.44)mmol/L,二组差异具有统计学意义(P<0.05);观察组孕妇2h血糖(6.50±1.67)mmol/L,对照组(5.89±1.00)mmol/L,二组差异具有统计学意义(P<0.05);观察组糖耐量异常者17例,对照组糖耐量异常者4例,二组差异具有统计学意义(P<0.05)。观察组孕妇总胆固醇(5.45±1.23)mmol/L、甘油三脂(2.51±1.24)mmol/L、高密度脂蛋白(1.71±0.38)mmol/L、低密度脂蛋白(3.47±0.89)mmol/L,而对照组分别为(4.86±0.92)mmol/L、(1.83±1.10)mmol/L、(1.54±0.26)mmol/L、(2.30±0.66)mmol/L,二组差异具有统计学意义(P<0.05)。结论妊娠中期彩超发现胎儿体重过大,结合孕妇血糖、血脂水平的检查,可以更好的对妊娠中期胎儿体重状况进行了解和评估,更好的对孕妇血糖,血脂水平进行评估,有利于早期发现妊娠期孕妇血糖、血脂情况,有利于孕妇安全度过妊娠期,促进胎儿更好的生长、发育。为临床早期诊断,治疗提供依据。
Objective To explore the relationship between fetal body weight and blood glucose in pregnant women in the second trimester. Methods 61 fetuses of gestational age from January 2015 to December 2016 in our hospital were enrolled in the study. The body weight of fetus in the second trimester of pregnancy was higher than that of the corresponding gestational age group. At the same time, 40 fetuses in the second trimester of pregnancy were matched with corresponding gestational weeks as control group, Fetal weight, at the same time detection of fasting blood glucose (FDG) in pregnant women, 2h postprandial blood glucose, total cholesterol, triglycerides, high density lipoprotein, low density lipoprotein levels. Results The body weight of the observation group was (1 010.93 ± 57.56) g and that of the control group (859.18 ± 58.27) g, the difference between the two groups was statistically significant (P <0.05). The body weight of pregnant women in observation group was 18.87 ± 2.87 g (4.20 ± 4.48) g, the difference between the two groups was statistically significant (P <0.05). The fasting blood glucose (FDG) in the observation group was 4.92 ± 0.58 mmol / L, (P <0.05). The blood glucose (2.50 ± 1.67 mmol / L) and the control group (5.89 ± 1.00) mmol / L in the control group were significantly higher than those in the control group (P <0.05). The difference between the two groups was statistically significant (P < 17 cases of abnormal glucose tolerance in the observation group, 4 cases of abnormal glucose tolerance in the control group, the difference between the two groups was statistically significant (P <0.05). The total cholesterol (5.45 ± 1.23) mmol / L, triglyceride (2.51 ± 1.24) mmol / L, high density lipoprotein (1.71 ± 0.38) mmol / L and low density lipoprotein (3.47 ± 0.89) mmol / L, while the control group were (4.86 ± 0.92) mmol / L, (1.83 ± 1.10) mmol / L, (1.54 ± 0.26) mmol / L and (2.30 ± 0.66) mmol / L respectively (P <0.05). Conclusion In the second trimester of pregnancy, we found that the fetus was overweight. Combined with the blood glucose and blood lipid levels of pregnant women, we can better understand and assess the fetal weight status in the second trimester of pregnancy and better evaluate the blood glucose and blood lipid levels in pregnant women, which is beneficial to early detection Pregnant women during pregnancy blood glucose, blood lipids, is conducive to the safety of pregnant women through pregnancy, and promote better fetal growth and development. For early clinical diagnosis and treatment provide the basis.