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目的探索糖尿病(DM)合并与未合并代谢综合征(MS)时各并发疾病的变化情况。方法采用回顾法,将我院2002年1月~2005年7月收治的DM患者资料进行整理和统计。结果DM合并MS的发病率为80.1%。DM合并与未合并MS各并发疾病的发病率比较:血脂紊乱:59.2%、38.6%(P<0.001);超重或肥胖:56.6%、34.3%(P<0.001);高血压:53.7%、30.7%(P<0.001);冠心病:59.4%、29.3%(P<0.001);心肌梗死:8.5%、3.6%(P<0.05);脑梗死:14.9%、7.9%(P<0.05);脑出血:8.7%、3.6%(P<0.05);病死率:4.8%、0.7%(P<0.05)。DM病程5~年新增MS发病率最高为33.7%。60~岁年龄段DM并发MS发病率最高为91.1%。结论DM合并与未合并MS比较,血脂紊乱、超重或肥胖、高血压、冠心病的发病率极度上升(P<0.001);心肌梗死、脑梗死、脑出血、病死率上升幅度没有以上并发疾病高,但也有明显上升(P<0.05)。
Objective To explore the changes of various concurrent diseases in diabetic (DM) patients with and without metabolic syndrome (MS). Methods Using the retrospective method, the data of DM patients admitted to our hospital from January 2002 to July 2005 were collected and statistically analyzed. Results The incidence of DM combined with MS was 80.1%. Comparisons of the morbidity rates of various concurrent diseases with and without MS: Dyslipidemia: 59.2%, 38.6% (P <0.001); Overweight or obesity: 56.6%, 34.3% (P <0.001); Hypertension: 53.7%, 30.7 (P <0.001); Coronary heart disease: 59.4%, 29.3% (P <0.001); Myocardial infarction: 8.5%, 3.6% (P <0.05); Cerebral infarction: 14.9%, 7.9% Bleeding: 8.7%, 3.6% (P <0.05); mortality: 4.8%, 0.7% (P <0.05). DM course of 5 years to add the highest incidence of MS was 33.7%. The incidence of DM complicated by MS in 60 ~ age group was 91.1%. Conclusion The incidences of dyslipidemia, overweight or obesity, hypertension and coronary heart disease were significantly higher in patients with DM combined with those without MS (P <0.001). There was no significant increase in the incidence of myocardial infarction, cerebral infarction, cerebral hemorrhage and mortality , But also significantly increased (P <0.05).