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例1:男,66岁。1972年左上腹发现痞块。1984年贫血加重,下肢骨痛入院。检查:重度贫血貌,肝肋缘下3cm,脾肋缘下12cm。Hb20g/L,WBC2.7×10~9/L,血片可见泪滴样红“细胞及少量晚幼粒。N-ALP积分明显增高。循坏血免疫复合物(CIC)28000D值(正常<800OD值)。血清IgG24.9g/L)。骨穿2次“干抽”。骨髓活检病理符合骨髓纤维化(CPM)。经康力龙等治疗贫血无改善,每月输血600ml。改用硫唑嘌呤50mg/日,2周后下肢疼痛减轻,用药50天一直未输血,Hb上升至65g/L。例2:男,55岁。左上腹胀痛,四肢骨痛一年。检查:贫血貌。肝肋缘下2cm,脾肋缘下15cm。Hb60g/L, WBC4.3×10~9/L,血片可见泪滴样红细胞及
Example 1: Male, 66 years old. In 1972 the left upper abdomen found lumps. Anemia in 1984, lower extremity bone pain hospitalized. Check: severe anemia appearance, liver ribs under the edge of 3cm, 12cm under the spleen ribs. (P <0.01), the value of 28000D of circulating blood immune complex (CIC) was significantly higher than that of the control group (Hb20g / L and WBC2.7 × 10-9 / L, 800OD value). Serum IgG24.9g / L.) Bone wear 2 times “dry pumping.” Bone marrow biopsy consistent with myelofibrosis (CPM) .Thirty days after the treatment of anemia without improvement, blood transfusions 600ml. Use of azathioprine 50mg / day, 2 weeks after the lower extremity pain relief, medication has not been transfused for 50 days, Hb rose to 65g / L. Example 2: Male, 55 years old. Left upper quadrant pain, limb pain for one year. Margin 2cm, spleen under the edge of 15cm.Hb60g / L, WBC4.3 × 10 ~ 9 / L, visible red blood cells and tear-like red blood cells and