中草药注射剂中普遍加入吐温-80作为澄清剂或增溶剂。现就吐温-80的理化性质、药理活性及毒性综述如下。1 吐温-80的理化性质吐温-80是多元醇型非离子表面活性剂吐温类中的一种,为失水山梨醇脂肪酸酯(Span-80)与20～26个环氧乙烷缩合而成的醚酯物,其通式为C_(64)H_(124)O_(26),分子量为1309.7,呈黄色油状物,有特臭,味酸而苦,比重1.08,粘度(25℃)约600cps。本品与水、乙醇、醋酸乙酯及甲醇均可混合,其亲油亲水 Commonly used in Chinese herbal injection Tween -80 as a clarifying agent or solubilizer. Tween -80 now on the physical and chemical properties, pharmacological activity and toxicity are summarized below. 1 Tween-80 physical and chemical properties of Tween -80 is a polyol type nonionic surfactant Twain in one, sorbitan fatty acid ester (Span-80) and 20 to 26 ethylene oxide It has the general formula C_ (64) H_ (124) O_ (26) and the molecular weight of 1309.7 as a yellow oily substance, ° C) of about 600 cps. This product and water, ethanol, ethyl acetate and methanol can be mixed, the lipophilic and hydrophilic