论文部分内容阅读
目的调查贵州省江口土家族男性葡萄糖-6-磷酸脱氢酶(G6PD)缺陷症的基因频率。方法2002年10—11月随机选取227名江口当地土家族男性居民,采用四氮唑蓝(NBT)纸片定性法初筛G6PD缺陷症,G6PD/6PGD比值法定量确诊。结果对贵州省江口县227名土家族男性进行筛查,共检出17例G6PD缺陷阳性,其基因频率为0·0749。结论通过对贵州土家族G6PD缺乏症基因频率的调查和分析,初步了解了贵州省土家族G6PD缺乏症的分布特征。为该地区预防该疾病、指导临床、提高少数民族的素质及研究该民族起源提供了一定的依据。
Objective To investigate the genetic frequency of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Tujia nationality in Jiangkou, Guizhou Province. Methods A total of 227 Tujia male residents in Jiangkou were randomly selected from October to November in 2002. The G6PD deficiency was detected by using the NBT paper qualitative method. The G6PD / 6PGD ratio was quantitatively determined. Results A total of 227 Tujia men were screened in Jiangkou County, Guizhou Province. A total of 17 G6PD positive cases were detected. The frequency of this gene was 0.0749. Conclusions The frequency of G6PD deficiency in Tujia nationality in Guizhou Province is investigated and analyzed, and the distribution characteristics of G6PD deficiency in Tujia nationality in Guizhou Province are analyzed. It provides a certain basis for preventing the disease in the area, guiding clinical practice, improving the quality of ethnic minorities and studying the origin of the ethnic group.