本文作者用SwissSPF小鼠对纯度为99.3%的环己基磺酸盐(含2.1ppm的环己胺)、有6～7种杂质成分的糖精(含邻-甲苯磺酰胺0.5%)及经质谱仪验证杂质成份的环己胺进行了多代的毒性、致癌性、胚胎毒性和致畸性等项研究。每项实验共分8组:第1组,5%环己基磺酸盐,第2组2%环己基磺酸盐,第3组10:1的5%环己基磺酸盐和0.5%的糖精,第4组10:1的2%环己基磺酸盐和0.2%糖精,第5 The authors used SwissSPF mice on 99.3% purity cyclohexylsulfonate (containing 2.1ppm of cyclohexylamine), there are 6 to 7 kinds of impurity components of saccharin (containing o-toluenesulfonamide 0.5%) and mass spectrometer Validation of the impurity components of cyclohexylamine for many generations of toxicity, carcinogenicity, embryotoxicity and teratogenic and other items of research. Each experiment was divided into 8 groups: Group 1, 5% cyclohexylsulfonate, Group 2 2% cyclohexylsulfonate, Group 3 10: 1 5% cyclohexylsulfonate and 0.5% saccharin , 4% 10: 1 2% cyclohexylsulfonate and 0.2% saccharin, No. 5