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食管癌的预后近年来并未明显提高,以血管内皮生长因子及其受体为靶向的治疗方案正越来越多受到关注。全文就血管内皮生长因子分子生物学特性及其在不同食管癌病理类型中的表达,食管癌的血管内皮生长因子表达与其生物学特性,治疗和预后等问题做一综述。
The prognosis of esophageal cancer has not been significantly improved in recent years. Treatment programs targeting vascular endothelial growth factor and its receptors are receiving increasing attention. This article reviews the molecular biological characteristics of vascular endothelial growth factor and its expression in different pathological types of esophageal cancer, the expression of vascular endothelial growth factor in esophageal cancer and its biological characteristics, treatment and prognosis.