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目的了解浙江省市级疾病预防控制中心(疾控中心)实验室生物安全管理现状,制订实验室生物安全管理体系有效运行评估指标。方法对浙江省市级疾控中心实验室按调查表内容进行调查和统计分析。结果浙江省市级疾控中心虽然成立了生物安全委员会,制定了生物安全管理手册,但有8家单位对涉及病原微生物的实验活动未做过生物安全风险评估,5家单位未对实验人员建立健康档案等。实验室最可能出现生物安全问题的原因是实验人员安全意识不强、违反操作规程、个人不良习惯和存在侥幸心理等。结论通过实验室生物安全管理体系有效运行评估指标的制订,并应用于生物安全监督检查,提高疾控中心实验室生物安全管理水平。
Objective To understand the status quo of laboratory biosafety management in Zhejiang Provincial Centers for Disease Control and Prevention (CDC) and formulate the evaluation index for the effective operation of laboratory biosafety management system. Methods The investigation and statistical analysis were conducted on the contents of the questionnaire in Zhejiang Provincial CDC Laboratory. Results Although the municipal CDC established the Biosafety Committee and formulated the biosafety management manual, 8 units did not assess the biosafety risk for the experimental activities involving pathogenic microorganisms, and 5 units did not establish the biosafety management manual Health files and so on. The most likely cause of biosafety in laboratories is due to poor safety awareness among experimenters, violations of operating procedures, personal bad habits and the existence of chances. Conclusions The establishment of evaluation index for effective operation of laboratory biosafety management system and its application in biosafety supervision and inspection and improvement of biosafety management in CDC laboratories.