目的了解孕妇外周血微量元素的水平和变化趋势,为孕期保健提供可靠的依据。方法使用BH5100原子吸收光谱仪对本院收治的250例围产期保健的早孕期、中孕期和晚孕期的3组孕妇和100例正常对照进行全血钙、铁、锌、镁、铜的测定,比较3组对象的区别并做统计学分析。结果 3组受试者均存在各种微量元素的缺乏,其中以缺钙和镁最为常见。早孕组的锌、钙和镁的含量与正常对照相比差异有统计学意义。晚孕组的铁、钙和镁含量与正常对照相比差异有统计学意义(P<0.05)。结论孕妇在怀孕期必须补充一定量的微量元素,否则会影响胎儿的生长发育,具有一定的临床指导意义。 Objective To understand the levels and trends of trace elements in peripheral blood of pregnant women and provide a reliable basis for the health care during pregnancy. Methods Whole blood levels of calcium, iron, zinc, magnesium and copper were determined by BH5100 atomic absorption spectrometry in 250 pregnant women with perinatal care in the first trimester, middle trimester and third trimester, and 100 normal controls. The differences between the three groups were compared and analyzed statistically. Results There were all kinds of trace elements deficiency in all the three groups, of which calcium deficiency and magnesium were the most common. The contents of zinc, calcium and magnesium in the first trimester group were significantly different from those in the normal control group. The contents of iron, calcium and magnesium in the control group were significantly different from those in the control group (P <0.05). Conclusion Pregnant women must be supplemented with a certain amount of trace elements during pregnancy, otherwise it will affect the growth and development of the fetus, which has a certain clinical significance.