建立了高效液相色谱法测定抗骨增生胶囊中柚皮苷的含量。采用Diamonsil C18柱,流动相为甲醇-2%冰乙酸(37∶63),检测波长283 nm,流速1.0 ml/min,柱温为30℃。柚皮苷浓度在40～200 g/ml范围内与峰面积的线性关系良好(r=0.999 6),平均加样回收率为100.17%(RSD 0.94%)。 A high performance liquid chromatography was developed for the determination of naringin in Kangguoshen Capsule. Diamonsil C18 column was used. The mobile phase was methanol-2% acetic acid (37:63). The detection wavelength was 283 nm, the flow rate was 1.0 ml / min and the column temperature was 30 ℃. The linear relationship between naringin concentration and peak area in the range of 40-200 g / ml was good (r = 0.999 6). The average recovery was 100.17% (RSD 0.94%).