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目的:评价血浆置换治疗慢性重型肝炎的疗效和影响疗效的因素,探讨合适的治疗时机。方法:在内科综合治疗的基础上进行血浆置换治疗30例慢性重型肝炎患者,分析并探讨疗效、影响疗效的因素及治疗时机。结果:30例患者治愈或好转17例,有效率为56.67%。血浆置换治疗对慢性重型肝炎晚期的患者疗效较差。有效率不随血浆置换治疗的次数增加而增高。患者合并的并发症越多疗效越差。结论:血浆置换是一种治疗慢性重型肝炎的有效方法,提高慢性重型肝炎治疗有效率需早期治疗,积极防治并发症。
Objective: To evaluate the efficacy of plasma exchange in the treatment of chronic severe hepatitis and the factors influencing the curative effect, and to explore the suitable timing of treatment. Methods: Thirty patients with chronic severe hepatitis were treated with plasma exchange on the basis of comprehensive medical treatment. The curative effect, factors affecting the curative effect and the timing of treatment were analyzed and discussed. Results: Thirty patients were cured or improved in 17 cases, the effective rate was 56.67%. Plasma exchange therapy is less effective in patients with advanced disease of chronic severe hepatitis. Efficacy does not increase with the number of plasma exchange treatments. Patients with more complications compounded the worse. Conclusion: Plasma exchange is an effective method for the treatment of chronic severe hepatitis. To improve the treatment efficiency of chronic severe hepatitis, we need early treatment and active prevention and treatment of complications.