患者女,67岁。四肢、颈部丘疹1年,伴血糖升高。皮疹呈环状扩大,中央消退,周边隆起。皮损组织病理示:真皮内可见胶原纤维、弹力纤维变性,黏蛋白沉积,组织细胞及多核巨细胞呈栅栏状排列。诊断:泛发型环状肉芽肿合并糖尿病。 Female patient, 67 years old. Limbs, neck, papules for 1 year, with elevated blood sugar. Rash was ring-like enlargement, the central subsided, the surrounding bulge. Pathological lesions showed: Collagen fibers can be seen in the dermis, elastic fiber degeneration, mucin deposition, tissue cells and multinucleated giant cells arranged in a grid-like manner. Diagnosis: Pancreatic type granuloma with diabetes.