糖尿病人下肢疼痛主要原因之一是并发周围神经炎。特点为感觉神经受累较早[1] ,以肢体自发性疼痛麻木等为突出的临床表现。病情常随糖尿病病程的延长及长期血糖控制欠佳而加重。大量的临床观察也发现 ,其疼痛症状的改善并不完全与血糖控制程度成正比 ,甚至部分患者于血糖控制后 One of the major causes of lower extremity pain in diabetic patients is peripheral neuritis. Characterized by sensory nerve involvement earlier [1], with numbness of limbs as the outstanding clinical manifestations. The condition often aggravates with the prolongation of the course of diabetes and the long-term poor glycemic control. A large number of clinical observations also found that the improvement of the pain symptom is not completely proportional to the degree of glycemic control, and even some patients after glycemic control