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目的分析血脂检验在心脑血管病诊治中的临床应用价值。方法选取医院收治的心血管疾病患者30例为心血管组,脑血管疾病患者30例为脑血管组以及同期体检健康成年人60例作为对照组,对比观察3组血脂水平,包括总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白(Apo B、Apo A-1)。记录3组血液流变学指标水平,包括血浆黏度、RBC聚集指数及RBC变形性。结果心血管组与脑血管组患者TC、TG、LDL-C、Apo B水平均高于对照组,而HDL-C、Apo A-1水平均低于对照组,差异均有统计学意义(P<0.05),但心血管组与脑血管组各血脂指标水平比较差异无统计学意义(P>0.05)。心血管组和脑血管组患者血浆黏度、RBC聚集指数均明显高于对照组,RBC变形性均弱于对照组,差异均有统计学意义(P<0.05),心血管组和脑血管组患者血浆黏度、RBC聚集指数、变形性比较差异均无统计学意义(P>0.05)。结论血脂检验在心脑血管疾病患者诊治时有着重大的临床意义,可考虑作为诊断心脑血管疾病的一项临床参考依据。
Objective To analyze the clinical value of serum lipids in the diagnosis and treatment of cardiovascular and cerebrovascular diseases. Methods Thirty patients with cardiovascular diseases admitted to the hospital were selected as the cardiovascular group, 30 patients with cerebrovascular disease as the cerebrovascular group, and 60 healthy adults during the same period as the control group. The levels of total cholesterol (TC TG, HDL-C, LDL-C, Apo B and Apo A-1 were measured. Three groups were recorded blood rheology indicators, including plasma viscosity, RBC aggregation index and RBC deformability. Results The levels of TC, TG, LDL-C and Apo B in patients with cardiovascular and cerebrovascular diseases were significantly higher than those in controls, while the levels of HDL-C and Apo A-1 were lower than those in controls <0.05). However, there was no significant difference in blood lipid levels between cardiovascular and cerebrovascular groups (P> 0.05). The plasma viscosity and RBC aggregation index of patients in cardiovascular and cerebrovascular groups were significantly higher than those in control group, and the degeneration of RBC was weaker than that in control group (P <0.05). The cardiovascular and cerebrovascular groups There were no significant differences in plasma viscosity, RBC aggregation index and deformability (P> 0.05). Conclusion The blood lipid test has great clinical significance in the diagnosis and treatment of patients with cardiovascular and cerebrovascular diseases, and can be considered as a clinical reference for the diagnosis of cardiovascular and cerebrovascular diseases.