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目的进一步探讨甲状腺嗜酸细胞肿瘤的临床诊断和治疗。方法分析2001-2007年上海交通大学医学院附属瑞金医院外科诊治15例甲状腺嗜酸细胞肿瘤的临床资料、手术方式和苏木精伊红染色(HE)切片结果。结果14例经病理证实为嗜酸细胞腺瘤,1例为一侧嗜酸细胞腺瘤合并对侧嗜酸细胞腺癌。术中冰冻切片仅有6例明确诊断,其余均依赖术后石蜡切片确诊。行患侧全切或近全切除3例,患侧次全切除12例。随访1～7年,中位随访时间38个月,无复发及死亡。结论甲状腺嗜酸细胞肿瘤有潜在恶性可能,手术是治疗嗜酸细胞肿瘤的有效手段。
Objective To further explore the clinical diagnosis and treatment of thyroid acidophilic tumor. Methods The clinical data, surgical procedures and hematoxylin and eosin staining (HE) results of 15 cases of thyroid acidophilic tumor diagnosed and surgically treated in Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine from 2001 to 2007 were analyzed. Results 14 cases were pathologically confirmed as eosinophilic adenoma, 1 case of one side of acidophilic adenoma with contralateral eosinophilic adenocarcinoma. Intraoperative frozen section only 6 cases a clear diagnosis, the rest are dependent on the paraffin section confirmed. All patients underwent total or near total resection in 3 cases and ipsilateral subtotal resection in 12 cases. Followed up for 1 to 7 years, the median follow-up time of 38 months, no recurrence and death. Conclusion Thyroid eosinophilic tumors are potentially malignant. Surgery is an effective method to treat eosinophilic tumors.