肾小球系膜细胞 (ＧＭＣ)是肾小球中功能最活跃的一类细胞 ,其具有多种功能 ,如分泌细胞基质 ,产生细胞因子 ,吞噬清除大分子物质及类似平滑肌细胞的收缩功能[1 ] 。因此ＧＭＣ的体外培养是研究肾小球疾病的发生、发展必不可少的手段之一[2 ] 。近年来我国多家实验室成功的培养 Glomerular mesangial cells (GMCs) are the most actively activated type of cells in the glomerulus and have multiple functions such as secretion of cell matrix, production of cytokines, phagocytosis of macromolecular substances and contraction of smooth muscle cells [ 1 ] . Therefore, GMC in vitro culture is to study the occurrence of glomerular disease, an indispensable means of development [2]. In recent years, many laboratories in our country have been successfully trained