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目的:探讨高压氧(HBO)辅助治疗胎儿生长受限(FGR)的临床疗效。方法:选取2017年6月至2019年6月在甘肃省妇幼保健院进行治疗的110例FGR孕妇作为研究对象，采用随机数字表法按1∶1分为观察组和对照组，每组55例。其中对照组采用低分子肝素联合阿司匹林进行常规治疗，观察组在对照组治疗的基础上进行HBO治疗，共治疗6周。采用彩色多普勒超声仪检测胎儿的生长情况，比较治疗前后的临床疗效和胎儿血流动力学指标，统计孕妇的妊娠合并症及新生儿出生状况等，并分析治疗前后孕妇的凝血功能。结果:观察组患者治疗有效率(83.64%)明显高于对照组(63.64%)，差异有统计学意义(n χ2＝5.666，n P＝0.017)；2组患者治疗后收缩期血流高值/舒张期血流高值(S/D)、阻力参数(RI)、动力参数(PI)均较治疗前均明显下降(n P<0.01)，且观察组治疗后S/D、RI、PI均低于对照组(n P0.05)。2组患者治疗后凝血功能指标较治疗前均明显改善，差异有统计学意义(n P0.05)。n 结论:HBO联合阿司匹林和低分子肝素治疗FGR，显著改善胎儿血流动力学参数改善，提高临床疗效。“,”Objective:To analyze the effect of hyperbaric oxygen (HBO) assisted treatment on fetal growth restriction (FGR).Methods:A total of 110 pregnant women with FGR admitted in Gansu Provincial Maternity and Child-care Hospital from June 2018 to June 2019 were selected as research objects. They were randomly divided into observation group and control group in a ratio of 1∶1, with 55 cases in each group. The control group was treated with low molecular heparin combined with aspirin, and the observation group was treated with HBO on the basis of the treatment of the control group for 6 weeks. The fetal growth was examined by color Doppler ultrasound. The clinical effect and fetal hemodynamic parameters before and after treatment were compared. The maternal and infant outcomes such as complications of pregnancy and neonatal conditions were statistically analyzed. The coagulation functions of pregnant women before and after treatment were also analyzed.Results:The effective rate of the observation group (83.64%) was significantly higher than that of the control group (63.64%) with statistical difference (n χ2=5.666, n P=0.017). After treatment, the high systolic blood flow/late diastolic blood flow (S/D), resistance index (RI), and pulse index (PI) of the two groups were all remarkably decreased (n P<0.01), and those of the observation group were lower than those of the control group (n P0.05). The coagulation function index of both two groups after treatment were all improved than those before treatment with statistically significant difference (n P0.05).n Conclusion:HBO combined with aspirin and low molecular heparin in the treatment of FGR can significantly improve the fetal hemodynamic parameters, and therefore improve the clinical efficacy.