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目的:观察香附四物汤对原发性痛经患者的临床疗效及对患者凝血功能的影响。方法:根据就诊单双号将山西医科大学第一附属医院和山西省妇幼保健院妇科门诊治疗的300例原发性痛经患者分为两组,每组各150例,对照组均给予非甾体类抗炎药联合月月舒颗粒,观察组患者给予非甾体类抗炎药联合香附四物汤,共治疗3个月经周期。结果:观察组疼痛VAS评分在治疗1、2、3个月经周期后显著低于对照组(P<0.05)。治疗3个月经周期后,观察组患者各中项医症状积分及总积分、凝血酶原时间(PT)、国际标准化比率(INR)、凝血活酶时间(APTT)改善显著优于对照组(P<0.05),愈显率(74.67%)显著高于对照组(63.33%)(P<0.05)。结论:香附四物汤治疗原发性痛经患者疗效确切,能有效改善患者凝血功能指标。
Objective: To observe the clinical efficacy of Xiangfu Siwu Decoction on patients with primary dysmenorrhea and its effect on coagulation function. Methods: 300 cases of primary dysmenorrhea treated by the First Affiliated Hospital of Shanxi Medical University and Maternal and Child Health Hospital of Shanxi Medical University were divided into two groups according to the single and double numbers of treatment. Each group had 150 cases. The control group were given non-steroidal Anti-inflammatory drugs combined with Yue Shu Shu particles, the observation group of patients given non-steroidal anti-inflammatory drugs combined with Fu Si Si Wu Tang, a total of 3 menstrual cycles. Results: The pain VAS score of the observation group was significantly lower than that of the control group after treatment for 1, 2, 3 months (P <0.05). After 3 menstrual cycles, the improvement of symptom score and total score, PT, INR, APTT in observation group were significantly better than those in control group (P <0.05). The cure rate (74.67%) was significantly higher than that of the control group (63.33%) (P <0.05). Conclusion: Xiang Fu Si Wu Tang treatment of patients with primary dysmenorrhea curative effect is exact, can effectively improve the coagulation function in patients with indicators.