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  5. Recombinant AAV-mediated Expression of Human BDNF Protects Neurons against Cell Apoptosis in Aβ-indu

Recombinant AAV-mediated Expression of Human BDNF Protects Neurons against Cell Apoptosis in Aβ-indu

来源 :华中科技大学学报：医学英德文版 | 被引量 : 0次 | 上传用户：eg
【摘 要】
：
The human brain-derived neurotrophic factor (hBDNF) gene was cloned by polymerase chain reaction and the recombinant adeno-associated viral vector inserted with
【作 者】
：
刘朝晖 马东亮 冯改丰 马延兵 胡海涛 
【机 构】
：
DepartmentofAnatomyandHistology-EmbryologySchoolofMedicineKeyLaboratoryofEnvironmentandGenesRelatedt
【出 处】
：
华中科技大学学报：医学英德文版
【发表日期】
：
2007年3期
【关键词】
：
BRAIN-DERIVED NEUROTROPHIC factor ADENO-ASSOCIATED virus Alzheimer’s disease hip 
【基金项目】
：
a grant from Natural Sci-ences Foundation of Shaanxi Province, China (2003K10- G83-2)
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论文部分内容阅读
The human brain-derived neurotrophic factor (hBDNF) gene was cloned by polymerase chain reaction and the recombinant adeno-associated viral vector inserted with hBDNF gene (AAV-hBDNF) was constructed. Cultured rat hippocampal neurons were treated with Aβ2
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