临床药动学监护(Clinical PharmacokineticSurveillance)就是利用药动学方法指导临床合理用药。其目的在于使所用药物达到预期的疗效,并避免或最大程度地减轻其毒、副反应。这在应用有效剂量与中毒剂量非常接近的药物时,特别是对于老人、小儿及一些肝、肾功能衰退的患者借助药动学监护权衡如何用药,尤受当代临床界的注目。 Clinical Pharmacokinetic Surveillance is the use of pharmacokinetic methods to guide clinical rational use of drugs. Its purpose is to achieve the desired therapeutic effect of the drug used and to avoid or minimize its toxicity and side effects. This application of effective dose and toxic dose is very close to the drug, especially for the elderly, children and some liver and kidney dysfunction with pharmacokinetic monitoring weigh how to use drugs, especially the attention of the contemporary clinical community.