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作者用三苯氧胺(Tamoxifen)治疗了26例原发性男性不育症(无精子症除外)。对象和方法年龄26~41岁,平均32岁。婚期13~110个月,平均48个月。服药前精子数10×10~6/ml以下6例,10×10~6~30×10~6/ml 7例,30×10~6~50×10~6/ml 4例,正常9例;运动率在50%以上仅4例。分别在治疗前后测定血中LH、FSH、睾酮、催乳素、雌二醇的含量,及精子数量和运动率。以三苯氧胺枸橼酸盐20mg/日连续服用12周。结果治疗前精子数在30×10~6/ml以上的13例中,4例显著增加,1例改善;在30×10~6/
The authors treated 26 patients with primary male infertility (excluding azoospermia) with Tamoxifen. Subjects and methods Age 26 to 41 years old, average 32 years old. Wedding period 13 to 110 months, an average of 48 months. The number of spermatozoa before medication was 10 × 10 ~ 6 / ml in 6 cases, 10 × 10 ~ 6 ~ 30 × 10 ~ 6 / ml in 7 cases, 30 × 10 ~ 6 ~ 50 × 10 ~ 6 / ml in 4 cases, ; Exercise rate of 50% or more only 4 cases. The levels of LH, FSH, testosterone, prolactin and estradiol in blood were measured before and after treatment, and the number of sperm and exercise rate were measured. Take tamoxifen citrate 20mg / day for 12 weeks. Results Among the 13 cases with more than 30 × 10 ~ 6 / ml of sperm before treatment, 4 cases were significantly increased and 1 case improved. In 30 × 10 ~ 6 /