作者报告罕见的术后无菌性脂性脑膜炎２例，均因填塞于颅底手术缺损处的游离脂肪瓣坏死所致。两例均经迷路行听神经瘤切除术，以腹部脂肪瓣填塞手术缺损区。术后均出现持续性伤口脑脊液漏和剧烈头痛。ＣＴ证实为脑积水和广泛弥散性颅内脑脊液脂肪滴。２例最终均需行脑脊液分流 The authors report two cases of rare postoperative aseptic meningitis, both of which are due to the necrosis of the free fat flap that fills the skull base defect. Two cases were lost to acoustic neuroma resection, abdominal fat flap to fill the surgical defect area. Postoperative persistent cerebrospinal fluid leakage and severe headache occurred. CT confirmed as hydrocephalus and widespread diffuse intracranial cerebrospinal fluid lipid droplets. 2 cases eventually need cerebrospinal fluid shunt