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德意志联邦共和国自1962年使用Sabin三价口服脊髓灰质炎疫苗以来,脊髓灰质炎发病率显著下降。1961年报告4461例,1978～1983年每年不足10例,1985年只有2例。从开始使用活疫苗起,就进行所谓的疫苗相关脊髓灰质炎的发病率的讨论。根据WHO顾问小组制定的判定标准,1963～1984年发生疫苗相关病例累计27例,其中服苗病例21例,接触病例6例。对这些病例均做了病毒学和血清学试验。其中11例服苗者和5例接触者分离到脊髓灰质炎病毒,大多数服苗病例和4例接触病例至少有一型病毒血清阳转。服苗病例中,15人≤2岁,6人8～38岁;
The incidence of poliomyelitis has dropped significantly in the Federal Republic of Germany since the Sabin trivalent oral polio vaccine was introduced in 1962. 4461 cases were reported in 1961, less than 10 cases in 1978-1983 and only 2 cases in 1985. A discussion of the so-called incidence of vaccine-associated poliomyelitis follows from the beginning of live vaccine use. According to the criteria set by the WHO advisory group, 27 cases of vaccine-related cases occurred between 1963 and 1984, of which 21 cases were clothing and seedlings and 6 cases were contact cases. Virology and serology tests were performed on these cases. Poliovirus was isolated from 11 cases of vaccine and 5 cases of contact, and most cases of vaccine-resistant and 4 cases of at least one case of seropositivity seroconversion. Clothing cases, 15 people ≤ 2 years old, 6 8 to 38 years old;