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目的分析在早期糖尿病肾病诊断中糖化血红蛋白与尿微量白蛋白检测的作用。方法回顾性分析2014年9月至2016年9月于我院治疗的110例糖尿病患者临床资料设为观察组,另选我院体检科健康者100例设为对照组,再根据一般资料中观察组不同基值范围HbA1C情况分为低、中、高三组,对比患者HbA1C及U-mA1b水平、DN发病率。结果观察组HbA1C、U-mA1b水平均比对照组高(P<0.05);在观察组中,高值组的HbA1C、U-mA1b水平均比低、中值组高,且DN发病率41.38%均比低值组13.33%、中值组25.00%高(P<0.05)。结论糖化血红蛋白、尿微量白蛋白检测可用作诊断早期糖尿病肾病的敏感指标,为糖尿病肾病早期诊治提供指导作用。
Objective To analyze the role of glycated hemoglobin and urine microalbumin in the diagnosis of early diabetic nephropathy. Methods The clinical data of 110 diabetic patients treated in our hospital from September 2014 to September 2016 were retrospectively analyzed. 100 healthy subjects in our hospital were selected as the control group. According to the general data, HbA1C group with different base range was divided into low, medium and high groups, comparing the level of HbA1C and U-mA1b, the incidence of DN. Results The levels of HbA1C and U-mA1b in the observation group were higher than those in the control group (P <0.05). In the observation group, the levels of HbA1C and U-mA1b in the high value group were lower than those in the high value group, and the incidence of DN was 41.38% Both higher than the low value group of 13.33%, 25.00% of the median group (P <0.05). Conclusions Glycated hemoglobin and urine microalbumin can be used as a sensitive index in the diagnosis of early diabetic nephropathy and provide guidance for the early diagnosis and treatment of diabetic nephropathy.