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目的探讨晚期前列腺癌骨转移性疼痛的治疗方法。方法 2004年-2005年对12例确诊为前列腺癌且有多个部位骨转移灶伴有疼痛的患者,采用国产紫杉醇周60MG/M2,静脉注射,每周一次,连用3周,休息 1周,共使用6周。结果治疗后疼痛缓解率3个月为85％;6个月为74％。骨转移性病灶减少或缩小,可评价毒副反应8例,均可耐受。结论本组病例经紫杉醇周剂量化疗后疗效肯定,疼痛缓解较满意,且不良反应轻,患者生活质量明显改善,值得扩大病例进一步研究。
Objective To investigate the treatment of advanced prostate cancer with bone metastatic pain. Methods From 2004 to 2005, 12 patients diagnosed with prostate cancer who had multiple sites of bone metastases with pain were treated with domestic paclitaxel 60MG / M2 intravenously once a week for 3 weeks and 1 week for rest. A total of 6 weeks. Results The pain relief rate after treatment was 85% in 3 months and 74% in 6 months. Bone metastases reduce or reduce the lesion can be evaluated in 8 cases of toxicity, can be tolerated. Conclusion This group of patients after paclitaxel week dose chemotherapy efficacy is affirmation, the pain relief is satisfied, and the adverse reaction is light, the quality of life of the patient is obviously improved, it is worth to expand the case further study.