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目的探讨老年糖尿病患者合并无症状性脑梗死的临床特点及危险因素。方法2000-01～2004-10将广东省茂名市人民医院门诊及住院老年糖尿病并无症状性脑梗死38例为观察组,非糖尿病并无症状性脑梗死36例为对照组,比较两组头颅CT特点及血胆固醇、甘油三酯、体重指数、高密度脂蛋白、纤维蛋白原等指标。结果老年糖尿病组多灶性脑梗死与非糖尿病组之间的差异具有显著性,血胆固醇、高密度脂蛋白、纤维蛋白原、体重指数的差异亦有显著性。结论老年糖尿病并无症状性脑梗死以多灶性脑梗死多见,老年糖尿病合并高甘油三酯、高胆固醇、高密度脂蛋白降低、肥胖的患者易致无症状性脑梗死。
Objective To investigate the clinical features and risk factors of senile diabetic patients with asymptomatic cerebral infarction. Methods Thirty-eight patients with asymptomatic diabetes mellitus in outpatients and inpatients with diabetes mellitus in Maoming People’s Hospital of Guangdong Province from January 2000 to June 2004 were enrolled in the study. Thirty-six non-diabetic patients with asymptomatic cerebral infarction were selected as the control group. CT features and blood cholesterol, triglycerides, body mass index, high-density lipoprotein, fibrinogen and other indicators. Results The difference between multifocal cerebral infarction and nondiabetic group in elderly diabetic group was significant. The differences of blood cholesterol, high density lipoprotein, fibrinogen and body mass index were also significant. Conclusions Elderly patients with diabetes mellitus with asymptomatic cerebral infarction are more common with multifocal cerebral infarction. Elderly patients with diabetes mellitus complicated with high triglyceride, high cholesterol and high density lipoprotein are more likely to develop asymptomatic cerebral infarction.