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作者报道采用环孢菌素 A 治疗1例难治性严重再生障碍性贫血(aplastic anemia,AA)取得成功。患儿男,9岁,1982年春起皮肤易青肿,出现贫血。同年7月诊为重度 AA。血红蛋白29~60g/L,粒细胞数0.2~0.4 x 10~9/L,血小板数≤10×10~9/L,网织红细胞数多数为0。用康复龙75mg/d 和强的松40mg/d 治疗至11月无效。发生脑出血,虽频繁输注血小板,后遗右侧上下肢中度麻痹。11月15日血细胞
The authors report the successful use of cyclosporin A in the treatment of one refractory severe aplastic anemia (AA). Children male, 9 years old, the skin is easy to bruise in spring 1982, anemia. In July the same year as a diagnosis of severe AA. Hemoglobin 29 ~ 60g / L, the number of granulocytes 0.2 ~ 0.4 × 10 ~ 9 / L, the number of platelets ≤ 10 × 10 ~ 9 / L, the majority of reticulocytes 0. With rehabilitation dragon 75mg / d and prednisone 40mg / d treatment to be ineffective in November. Occurrence of cerebral hemorrhage, although frequent influx of platelets, paralysis of right and left upper limb paralysis. November 15 blood cells