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本文报告了外科治疗肺腺鳞癌102例,占同期肺癌的10%。临床特点为侵袭力强,早期转移,进展猛烈等低分化癌特征,其粘膜下浸润较远为其他类型肺癌所罕见。周围型肿瘤距支气管切缘1~5cm,组织学切缘受侵者达到25.3%;3、5年生存率为16.4%及8.9%,较其他类型肺癌明显偏低。因此可以认为其是一种预后最差的低分化混合癌。其腺、鳞癌两种恶性成分比例肿瘤大小有关即肿瘤越大,鳞癌成分越多。本文提供了肺腺鳞癌的诊断标准及其理由。早期诊断外科手术治疗效果良好,对中晚期病例应行以手术为主之综合治疗。
This article reports 102 surgical treatment of lung adenosquamous carcinoma, accounting for 10% of lung cancer in the same period. The clinical features are strong invasiveness, early metastasis, and fiercely advanced and poorly differentiated carcinomas. The submucosal infiltration is rare in other types of lung cancer. Peripheral tumors from the bronchial margin 1 ~ 5cm, histological margin of invaders reached 25.3%; 3,5-year survival rate was 16.4% and 8.9%, significantly lower than other types of lung cancer. Therefore, it can be considered as a poorly differentiated mixed cancer with the worst prognosis. The ratio of the two malignant components of the gland and squamous cell carcinoma is related to the size of the tumor, that is, the larger the tumor, the more squamous cell carcinoma components. This article provides diagnostic criteria for lung adenosquamous carcinoma and its rationale. Early diagnosis and surgical treatment is effective, and comprehensive treatment based on surgery should be performed for middle and late stage patients.