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烟胺羟丙茶碱与茜素红在水溶液中发生电行转移反应,生成2:1型络合物,此络合物的λmax=539nm,表观摩尔吸光系数是2.72×103L·mol-1·cm-1,药物浓度在5-150mg/L范围内符合比尔定律,相对标准偏差为0.81%(n=6),回收率在97%以上。应用拟定的方法测定药物制剂的含量,结果与紫外分光光度法一致。
Nicomine hydroxypropanic acid and alizarin red in aqueous solution occurred in the line transfer reaction, generating 2: 1 complex, the complex λmax = 539nm, the apparent molar absorptivity was 2.72 × 103L · mol -1 · cm -1. The Beer’s law was obeyed in the range of 5-150 mg / L with the relative standard deviation of 0.81% (n = 6) and the recovery of over 97%. Application of the proposed method for the determination of drug content, the results and UV spectrophotometry.