人类鼠伤寒沙门氏菌感染,近年来急剧上升,尤以小儿为甚。我们自1977年以来,分离出鼠伤寒沙门氏菌200余株,兹将资料完整的130株进行病原学的初步分析。临床概况及菌株来源本组病例均为住院病人,其中12岁以下的儿童75例。13～41岁的青壮年55例,主要症状和体征为发热、腹泻等。粪便呈黄绿色粘液状稀便或脓血便,临床初诊为“腹泻”或“菌痢”。但未培养出痢疾杆菌。本文所有鼠伤寒沙门氏菌菌株,均由上述病人粪便中分离而得,同一病例只选用首次菌株。细菌鉴定及药敏结果本菌为革兰氏阴性杆菌。在SS培养基上为微 Human Salmonella typhimurium infection, a sharp rise in recent years, especially children. Since 1977, we have isolated more than 200 Salmonella typhimurium strains, and we have conducted a preliminary etiological analysis of the 130 strains. Clinical profiles and sources of strains in this group of patients were hospitalized patients, including children under the age of 12 75 cases. 55 cases of young adults aged 13 to 41 years old, the main symptoms and signs of fever, diarrhea and so on. Stool was yellowish green mucus-like loose stools or purulent blood, clinical first visit as “diarrhea” or “bacillary dysentery”. But did not cultivate Shigella. All Salmonella typhimurium strains in this paper were isolated from the stool in the above patients, the same case only selected the first strain. Bacterial identification and drug susceptibility The bacteria is Gram-negative bacilli. On SS medium is micro