2012年新疆维吾尔自治区人群棘球蚴病流行病学调查

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目的了解棘球蚴病在新疆维吾尔自治区(简称新疆)人群的流行情况,为实行分类指导、制定适合新疆特点的防治规划提供科学依据。方法于2012年3-10月以新疆14地(州)的92个县(市、区)为调查单位,每个调查单位选择农业、牧业、半农牧业和城镇4个乡(镇、场)为调查点,在每个乡(镇、场)调查全年龄组人群800人,每县共调查3 200人。采用腹部B超检查进行诊断,对疑似病例辅以血清学抗体检测。结果全区共调查293 140人,棘球蚴病患病率为0.14%(407/293 140)。其中,北疆地区患病率为0.18%(290/158 985),占总病例数的71.25%(290/407),南疆地区患病率为0.09%(117/134 155)占总病例数的28.75%(117/407),两个地区的患病率间差异有统计学意义(P<0.05)。病例主要分布在乌鲁木齐市(19.90%,81/407)、塔城地区(13.27%,54/407例)、伊犁哈萨克自治州(13.02%,53/407)和昌吉回族自治州(9.83%,40/407),占病例总数的56.02%(228/407)。蒙古族和柯尔克孜族患病率较高,分别为0.42%(21/5 045)和0.35%(32/9 045),均高于其他民族(0.07%~0.22%)(P<0.05)。男性和女性患病率分别为0.13%(195/144 715)和0.14%(212/148 425),两者差异无统计学意义(P>0.05)。0~9岁年龄组患病率最低,为0.07%(7/10 754),70~79岁和80~99岁年龄组患病率较高,分别为0.27%(33/12 310)和0.28%(7/2 461),患病率随年龄增大呈上升趋势;在年龄构成上,以30~49岁人群为多(43%,175/407)。文盲人群的患病率最高,为0.25%(39/15 470),高于其他人群(0.06%~0.14%)(P<0.05)。牧民患病率最高,为0.29%(63/22 074),高于其他职业人群(0.00%~0.13%)(P<0.05)。牧区、农区、半农半牧区和城镇的患病率分别为0.16%(70/44 247)、0.16%(181/113 016)、0.12%(88/70 610)和0.10%(68/65 267),其中城镇患病率最低,与牧区和农区患病率间差异有统计学意义(P<0.05)。结论新疆人群棘球蚴病流行范围广,主要分布在北疆地区。 Objective To understand the prevalence of echinococcosis in Xinjiang Uygur Autonomous Region (hereinafter referred to as Xinjiang), and to provide a scientific basis for the implementation of classification guidance and formulation of prevention and control plans suitable for Xinjiang. METHODS: From March to October 2012, 92 counties (cities and districts) of 14 prefectures and cities in Xinjiang were selected as the investigation units. Each survey unit selected 4 townships (towns, villages, towns and villages) Field) as survey sites, 800 people of all age groups were surveyed in each township (town and field), and a total of 3,200 people were investigated in each county. Abdominal B-ultrasound diagnosis, supplemented by suspected cases of serological antibody testing. Results A total of 293 140 people were surveyed in the district. The prevalence of hydatid disease was 0.14% (407/293 140). Among them, the prevalence in northern Xinjiang was 0.18% (290/158 985), accounting for 71.25% (290/407) of the total number of cases and 0.09% (117/134 155) in southern Xinjiang. The total number of cases Of 28.75% (117/407). There was significant difference between the two regions (P <0.05). The cases were mainly distributed in Urumqi (19.90%, 81/407), Tacheng (13.27%, 54/407), Ili Kazakh Autonomous Prefecture (13.02%, 53/407) and Changji Hui Autonomous Prefecture (9.83%, 40/407) ), Accounting for 56.02% (228/407) of the total number of cases. The prevalence rates of Mongolian and Kirgiz were 0.42% (21/5 045) and 0.35% (32/9 045), respectively, higher than other nationalities (0.07% -0.22%) (P <0.05). The prevalence rates of males and females were 0.13% (195/144 715) and 0.14% (212/148 425), respectively, with no significant difference (P> 0.05). The lowest prevalence rate in 0-9 years old group was 0.07% (7/10 754). The prevalence rate in the age group of 70-79 years and 80-99 years old was 0.27% (33/12 310) and 0.28 % (7/2 461). The prevalence increased with age. In the age group, the prevalence was higher in people aged 30-49 (43%, 175/407). The illiterate population had the highest prevalence of 0.25% (39/15 470), higher than the other population (0.06% -0.14%) (P <0.05). The highest incidence of herdsman was 0.29% (63/22 074), which was higher than that of other occupational groups (0.00% -0.13%) (P <0.05). The prevalence rates in pastoral areas, agricultural areas, semi-agricultural and semi-pastoral areas and urban areas were 0.16% (70/44 247), 0.16% (181/113 016), 0.12% (88/70 610) and 0.10% (68/65 267). Among them, the lowest prevalence in urban areas was found, which was significantly different from the prevalence rates in pastoral areas and rural areas (P <0.05). Conclusion The prevalence of hydatid disease in Xinjiang is wide and mainly distributed in northern Xinjiang.
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