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目的 :比较无肌病性皮肌炎(ADM)和皮肌炎(DM)患者肺间质病变(ILD)的临床特点及预后差异。方法 :对2005年3月—2012年8月该院皮肤科收治的11例ADM-ILD患者和37例DM-ILD患者的临床资料进行回顾性分析。结果:与DM患者比较,ADM患者发生急性ILD者更多,ADM-ILD患者氧合指数(Pa O2/Fi O2)比值较低,急性者更多见,且死亡率较高。结论 :Pa O2/Fi O2比值可作为ADM-ILD患者预后不良的指标之一。
Objective: To compare the clinical features and prognosis of interstitial lung disease (ILD) between myopathy-free dermatomyositis (ADM) and dermatomyositis (DM). Methods: The clinical data of 11 patients with ADM-ILD and 37 patients with DM-ILD admitted to the Department of Dermatology from March 2005 to August 2012 were analyzed retrospectively. Results: Compared with DM patients, there were more acute ILDs in ADM patients and lower Pa O2 / Fi O2 ratio in ADM-ILD patients, which were more common in acute cases and higher in mortality rate. Conclusion: Pa O2 / Fi O2 ratio may be one of the indicators of poor prognosis in patients with ADM-ILD.