众所周知 ,硝基化合物是一类强致癌物 ,在进行有关其毒性和降解的研究中 ,需用到 2 ,3-二硝基甲苯。在参考了国内外有关文献 [1,2 ] 的基础上 ,我们设计了以邻甲基苯胺为起始原料 ,先经过硝化反应得到 2 -甲基 - 6-硝基苯胺 ,再经重氮化和 Sandmeyer反应 ,用硝基置换重氮盐基 , It is well-known that nitro compounds are a class of strong carcinogens and require 2,3-dinitrotoluene for studies on their toxicity and degradation. Based on the reference of domestic and foreign literatures [1, 2], we designed o-methylaniline as the starting material to obtain 2 - methyl - 6 - nitroaniline by nitration and diazotization And Sandmeyer reaction, replace the diazo salt with nitro,