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目的观察依达拉奉和奥扎格雷钠联合应用治疗急性脑梗死的疗效。方法将60例急性脑梗死患者分为治疗组和对照组各30例。对照组给予血栓通注射液20ml加入生理盐水250ml静脉滴注,1次/d,连用14d,奥扎格雷钠80mg加入生理盐水500ml静脉滴注,1次/d,连用14d;治疗组在此基础上加用依达拉奉30mg加入生理盐水100ml,2次/d静脉滴注,连用14d。观察两组患者治疗前后的疗效和临床神经功能缺损程度评分。结果治疗组显效率、总有效率、神经功能缺损程度评分与对照组比较,差异均有统计学意义,(P<0.01),两组均无明显不良反应。结论依达拉奉和奥扎格雷钠联合治疗急性脑梗死疗效确切,无不良反应。
Objective To observe the therapeutic effect of edaravone and ozagrel combined on acute cerebral infarction. Methods 60 patients with acute cerebral infarction were divided into treatment group and control group of 30 cases. The control group was given Xueshuantong injection 20ml saline 250ml intravenous infusion, 1 time / d, once every 14d, 80mg sodium ozagrel added saline 500ml, 1 / d, once every 14d; the treatment group based on this Add edaravone 30mg by adding saline 100ml, 2 times / d intravenous infusion, once every 14d. The curative effect and clinical neurological deficit scores of two groups before and after treatment were observed. Results The effective rate, total effective rate and neurological deficit score of the treatment group were significantly different from those of the control group (P <0.01). There was no significant adverse reaction in both groups. Conclusion The combination of edaravone and ozagrel sodium in the treatment of acute cerebral infarction is effective and has no adverse reactions.