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新生儿窒息缺氧常引起神经、呼吸、心血管、胃肠道和肾脏等多系统、多脏器损害。窒息新生儿的预后主要决定于脑及全身器官损伤程度。本研究通过对窒息新生儿血浆前列环索(Prostacyclin,PGI_2)和血栓素A_2(Thromboxane A_2,TxA_2)测定,观察其水平变化与器官功能损害的关系,为临床治疗提供一些理论依据。对象和方法一、对象1．窒息组:本院新生儿病房和NICU病房1995年新入院窒息后新生儿80例,入院时龄16.25±7.42小时,其中轻度窒息41例,重度窒息39例。男47例,女33例。胎龄36~42周,平均38.8周;出生体重2350~3980克,平均3120克。
Asphyxia Neonatal hypoxia often cause nerve, respiratory, cardiovascular, gastrointestinal tract and kidneys and other multiple systems, multiple organ damage. The prognosis of neonatal asphyxia mainly depends on the degree of brain and body organ damage. In this study, the relationship between plasma levels of Prostacyclin (PGI_2) and Thromboxane A_2 (TxA_2) in neonatal asphyxia neonates was observed and the level of organ damage was observed to provide some theoretical evidence for clinical treatment. Objects and methods First, the object 1. Asphyxial group: In our hospital neonatal ward and NICU ward in 1995 new admission after asphyxia 80 newborns, admission age 16.25 ± 7.42 hours, of which 41 cases of mild asphyxia, severe asphyxia 39 cases. There were 47 males and 33 females. 36 to 42 weeks gestational age, an average of 38.8 weeks; birth weight 2350 ~ 3980 grams, an average of 3120 grams.