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目的探讨孤独症患者与胃肠失功能的关系。方法采用自制胃肠功能调查表对60例孤独症患者,60例精神发育迟滞(MR),60例正常对照组进行了比较。结果 1孤独症组胃肠失功能的发生率为43.33%,较MR组的21.66%和正常组的13.33%均显著为高(χ2=5.64,10.16;P<0.01,0.001);其中尤以慢性便秘、腹泻以及大便恶臭最为显著;2孤独症患者的症状越严重,胃肠失功能的发生率越高(χ2=8.869,P<0.01)。结论孤独症患者与胃肠失功能有关,伴有胃肠失功能的孤独症可能是孤独症谱系障碍的一个亚型。
Objective To investigate the relationship between autism and gastrointestinal failure. Methods Sixty cases of autism, 60 cases of mental retardation (MR) and 60 cases of normal control group were compared with homemade gastrointestinal function questionnaire. Results 1 The incidence of gastrointestinal dysfunction in autism group was 43.33%, significantly higher than 21.66% in MR group and 13.33% in normal group (χ2 = 5.64,10.16; P <0.01,0.001) Constipation, diarrhea and fecal stools were the most significant. 2 The more severe the autistic symptoms were, the higher the incidence of gastrointestinal dysfunction (χ2 = 8.869, P <0.01). Conclusions Autism patients are associated with loss of gastrointestinal function. Autism with gastrointestinal dysfunction may be a subtype of autism spectrum disorder.