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目的 观察白芍总苷对小鼠心肌耗氧量的影响。方法 采用整体氧耗动态观察中分离心肌氧耗方法。结果 给予白芍总苷 2 0mg/kg ,小鼠整体耗氧量和心肌耗氧量的变化明显低于生理盐水组和异丙肾上腺素组 (P <0 0 1 )。白芍总苷作用强度稍弱于阿替洛尔。结论 白芍总苷能明显降低心肌耗氧量
Objective To observe the effects of total glucosides of paeony on myocardial oxygen consumption in mice. Methods The method of myocardial oxygen consumption was observed by dynamic observation of total oxygen consumption. Results The total oxygen consumption and myocardial oxygen consumption of mice were significantly lower than those of normal saline group and isoproterenol group (P <0 01). The total glucosides of Paeonia lactiflora had a slightly weaker effect than atenolol. Conclusion Total glucosides of paeony can significantly reduce myocardial oxygen consumption