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本文对水质分析中亚硝酸盐的N-(1-萘基)-乙二胺分光光度法能否应用于测定0.5%甲硝唑注射液中亚硝酸盐含量进行了验证,并用于测定市售的四个不同厂家、不同批号0.5%甲硝唑注射液。其中亚硝酸盐(以NO_2~-计)浓度范围为2.2~7.3μg/ml,并且检查原料药中亚硝酸盐含量极微。
In this paper, the nitrite content of nitrite in water quality analysis can be applied to the determination of nitrite content in 0.5% metronidazole injection was verified and used to determine the commercial Of four different manufacturers, different batches of 0.5% metronidazole injection. The concentration of nitrite (calculated as NO 2 - -) ranged from 2.2 to 7.3 μg / ml, and the content of nitrite in raw materials was very low.