川畸病(KD)亦名粘膜皮肤淋巴结综合征,由日本川畸氏于1967年首次报道,1974年始见于英文文献,1977年才有耳鼻喉科文献报道。虽常见于东方人,但近年在美国发病率也增高,已渐为全球医生认识。其临床特征为一急性发热性多系统血管炎,有皮疹,结膜炎,非化脓性颈淋巴结肿大,口腔粘膜病变等,如未获及早确诊及合宜治疗,可发生严重的心血管并发症,死亡率约1～2%。KD的早期表现(颈淋巴结肿大及口腔病变)常使患者首诊于耳鼻喉科,故应对之有足够认识,以免误诊、误治,延误治疗时机。该作者复习1982～1990年8年间就诊于Virginia医学院的42例住院患者,大多为儿童,就诊时病程平均4.4年,黑人32例,白人9例,东方人1例,男26例,女16例,首诊时30例有非化脓性颈淋巴结炎,另5例于首诊后才出现 Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome, was first reported by Kawasaki in Japan in 1967 and was first documented in English in 1974, and was not reported in 1977 in ENT literature. Although common to Asians, the incidence in the United States has also risen in recent years and it has gradually become known to doctors in the world. The clinical features of an acute febrile multi-system vasculitis, rash, conjunctivitis, non-purulent cervical lymph nodes, oral mucosal lesions, such as without early diagnosis and appropriate treatment, may have serious cardiovascular complications, The mortality rate is about 1 ~ 2%. Early manifestation of KD (cervical lymph node enlargement and oral lesions) often make the patient first diagnosed with otolaryngology, it should be enough understanding, to avoid misdiagnosis, mistreatment, and delay the timing of treatment. The author reviewed 42 inpatients attending Virginia Medical College from 1982 to 1990, most of whom were children. The average duration of the visit was 4.4 years, 32 were black, 9 were white, 1 was Oriental, 26 were males and 16 were females For example, the first visit 30 cases of non-purulent cervical lymphadenitis, and the other 5 cases after the first visit appeared