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目的了解北京市上地医院围产儿出生缺陷流行病学特征及相关因素。方法按照中国出生缺陷监测中心1995年制定的出生缺陷诊断和统计标准,对上地医院2006年～2007年的围产儿出生缺陷监测资料进行回顾性分析。结果上地医院2006年～2007年共监测围产儿10956例,检出出生缺陷儿200例,出生缺陷发生总率为182.55万/。发生率在前5位的缺陷类型分别为为先天性心脏病(58.42万/)、外耳其他畸形(33.44万/)、多指/趾(28.29万/)、全唇裂(16.43/万)、尿道下裂(5.48万/)。对2006年～2007年出生缺陷进行比较,P<0.05,有统计学意义,显示出生缺陷发生率呈现上升趋势。对不同人群特征的出生缺陷发生率进行比较,显示出生缺陷的发生与胎数、婴儿性别、婴儿出生体重、分娩孕周、分娩结局有关(P<0.05)。结论根据出生缺陷的监测结果,采取综合干预措施,预防出生缺陷。
Objective To understand the epidemiological characteristics and related factors of birth defects in Shangdi Hospital of Beijing. Methods According to the diagnostic and statistical standards of birth defects established by China Center for Birth Defects Monitoring in 1995, the data of the monitoring of birth defects in perinatal children in Shangdi Hospital from 2006 to 2007 were analyzed retrospectively. Results On the hospital from 2006 to 2007, 10 956 perinatal patients were monitored, and 200 cases of birth defects were detected. The total incidence of birth defects was 1.8255 million. The incidence of defects in the top five were congenital heart disease (584200 /), other deformities of the outer ear (334400/), multiple finger toe (28299) /, full cleft lip (16.43 / million), urethra Under the split (54,800 /). The birth defects in 2006 ~ 2007 were compared, P <0.05, with statistical significance, showing that the incidence of birth defects showed an upward trend. Comparison of the incidence of birth defects among different population characteristics showed that the incidence of birth defects was related to the number of fetuses, the sex of the infants, the birth weight of the infants, gestational age of delivery and the outcome of delivery (P <0.05). Conclusions Based on the monitoring results of birth defects, comprehensive interventions are taken to prevent birth defects.