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目的拟探讨胰肾联合移植术后糖尿病并发肾功能衰竭患者生命质量的状况。方法回顾分析我院糖尿病并发肾功能衰竭患者的基本资料,同时用健康测量量表SF-36针对糖尿病伴发肾功能衰竭患者术前、术后2年、术后4年进行评估。结果 8例糖尿病并发肾功能衰竭患者除1例出现脑血管意外家人放弃治疗外,其他所有患者均恢复顺利,接受了平均时间为23.3月(1～56月)的随访。术后血糖、C肽、肌酐稳定。术后2年评分与术前相比较,SF-36八个维度的评分均有显著性改善(P<0.05),且基本与中国正常人群评分相似(P>0.05)。结论胰肾联合移植术能明显改善糖尿病并发肾功能衰竭患者的生命质量。
Objective To explore the status of quality of life in diabetic patients complicated with renal failure after pancreas-kidney combined transplantation. Methods The basic data of diabetic patients complicated with renal failure in our hospital were retrospectively analyzed. The patients with diabetes mellitus and renal failure were treated with SF-36 for 2 years and 4 years after operation. Results All 8 patients with diabetic patients with renal failure recovered except one case of cerebrovascular accident. All patients recovered smoothly and were followed up for an average of 23.3 months (ranged from 1 to 56 months). Postoperative blood glucose, C-peptide, creatinine stability. The score of 2-year postoperatively was significantly improved in eight dimensions of SF-36 compared with preoperative scores (P <0.05), and was similar to that of normal Chinese population (P> 0.05). Conclusions Pancreas-kidney combined transplantation can significantly improve the quality of life of diabetic patients with renal failure.