他汀类药是目前已知最强的调脂类药物,在心血管病的一级和二级预防中已取得了显著效果,近年来在缺血性卒中的防治中他汀类药物逐渐受到重视。本文就他汀类药物预防缺血性卒中的高质量证据、可能机制、安全性以及现状前景进行综述。1他汀类药物对缺血性卒中的预防作用在针对高危 Statins are the strongest lipid-lowering drugs known at present and have achieved remarkable results in the primary and secondary prevention of cardiovascular diseases. In recent years, statins have drawn increasing attention in the prevention and treatment of ischemic stroke. This review summarizes the high-quality evidence, potential mechanisms, safety and current status of statins in preventing ischemic stroke. 1 The preventive effect of statins on ischemic stroke is at high risk