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目的探讨血脂与结肠腺瘤的相关性。方法对128例结肠腺瘤患者和40例正常对照者,酶法测定血浆脂质水平。结果结肠腺瘤组血浆总胆固醇和甘油三酯水平分别为(5.30±0.90)mmol/L和(1.45±0.31)mmol/L,显著高于对照组的(4.30±0.60)mmol/L和(1.02±0.25)mmol/L;绒毛状腺瘤组血浆总胆固醇水平为(5.50±0.70)mmol/L,显著高于非绒毛状腺瘤组的(4.80±0.60)mmol/L;绒毛状腺瘤组血浆甘油三酯为(1.50±0.35)mmol/L,与非绒毛状腺瘤组(1.40±0.28)mmol/L的水平比较差异无统计学意义。结论血浆总胆固醇水平和甘油三酯水平增高与结肠腺瘤的发生有关。
Objective To investigate the relationship between blood lipids and colorectal adenomas. Methods 128 patients with colonic adenoma and 40 normal controls were enrolled in this study. Enzymatic determination of plasma lipid levels was performed. Results The levels of total cholesterol and triglyceride in the group of colon adenoma were (5.30 ± 0.90) mmol / L and (1.45 ± 0.31) mmol / L, respectively, which were significantly higher than those in the control group (4.30 ± 0.60 mmol / L and ± 0.25) mmol / L, while the total cholesterol level in villous adenoma group was (5.50 ± 0.70) mmol / L, which was significantly higher than that in non-villous adenoma group (4.80 ± 0.60 mmol / L) Plasma triglyceride was (1.50 ± 0.35) mmol / L, which was not significantly different from that of non-villous adenoma (1.40 ± 0.28) mmol / L. Conclusion The increase of plasma total cholesterol and triglyceride level is related to the occurrence of colonic adenomas.