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本研究对１０７７ 例不育门诊病人的精子进行顶体酶活性检测，并分析了某些因素对顶体酶活性的影响。研究发现，精子顶体酶活性呈正偏态分布，６５ ．５ ％ 低于正常值（１８ μ Ｉ Ｕ／１０６ 精子） ；相关检验表明，顶体酶活性与精子活率、活力呈显著正相关，与精子畸形率和镜下精液白细胞呈显著负相关；卡方检验表明，顶体酶活性与支原体感染、精浆抗精子抗体无关；秩和检验表明，顶体酶活性降低组精液粘度高于顶体酶活性正常组（ Ｐ＜ ０ ．０００５） 。
In this study, spermatozoa of 1077 infertile patients were tested for acrosin activity and the effects of some factors on acrosin activity were analyzed. The study found that sperm acrosin activity was positively skewed distribution, 65. 5% lower than the normal value (18 μ I U / 106 sperm); correlation test showed that acrosin activity and sperm motility, vitality was significantly positively correlated, and sperm deformity rate and microscopic leucovorin significantly negatively correlated; card The square test showed that acrosin activity was not associated with mycoplasma infection and seminal plasma anti-sperm antibody. The rank sum test showed that the sperm motility of the reduced acrosin activity group was higher than that of the normal acrosin activity group (P <0.0005).