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[Sabin S et al:Zbl Bakt Hyg I.AbtOrig A 249:254,1981(德文)] 以往一些试验表明,百日咳免疫球蛋白的临床效果存在疑问,是由于这一制品的抗体测定方法常常不够准确,不能评价免疫球蛋白抗体的凝集反应滴度与其小鼠被动保护力之间的相互关系。
[Sabin S et al: Zbl Bakt Hyg I. AbtOrig A 249: 254, 1981 (German)] Previous studies have shown that the clinical effect of pertussis immunoglobulin is questionable because the antibody assay method of this preparation is often not accurate enough , The correlation between the agglutination titer of the immunoglobulin antibody and the passive protective force of the mouse can not be evaluated.