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目的分析急性胰腺炎接受奥曲肽联合泮托拉唑钠治疗的效果。方法 64例急性胰腺炎患者随机分为对照组和观察组,各32例。对照组接受奥曲肽治疗,观察组接受奥曲肽联合泮托拉唑钠,分析两组治疗效果并比较两组的常见症状缓解时间、住院时间及实验室指标转阴时间。结果观察组的痊愈率高于对照组(53.13%VS 28.13%,P<0.05),但总有效率比较差异均无统计学意义(96.88%VS90.63%,P>0.05);与对照组相比,观察组的发热、腹胀、腹痛及呕吐的缓解时间,血淀粉酶、血脂肪酶、血清钙和尿淀粉酶的转阴时间及住院时间均较短,差异有统计学意义(P<0.05)。结论在奥曲肽治疗急性胰腺炎的基础上,加用泮托拉唑钠可提高治疗效果,并加快症状缓解和实验室指标转阴。
Objective To analyze the effect of octreotide combined with pantoprazole sodium on acute pancreatitis. Methods 64 cases of acute pancreatitis were randomly divided into control group and observation group, 32 cases in each. The control group received octreotide treatment. The observation group received octreotide combined with pantoprazole sodium. The therapeutic effect was compared between the two groups. The common symptom relief time, hospitalization time and laboratory index negative time were compared between the two groups. Results The cure rate of the observation group was higher than that of the control group (53.13% VS 28.13%, P <0.05), but the total effective rate was not significantly different (96.88% vs 90.63%, P> 0.05) In the observation group, the time of fever, bloating, abdominal pain and vomiting, the time of over-time and hospital stay of blood amylase, blood lipase, serum calcium and urine amylase were shorter, the difference was statistically significant (P <0.05 ). Conclusion On the basis of octreotide treatment of acute pancreatitis, the addition of pantoprazole sodium can improve the therapeutic effect, and accelerate the remission of symptoms and laboratory indicators negative.