论文部分内容阅读
目的:探讨和研究血清总胆汁酸测定对于乙型肝炎后肝硬化诊断的临床应用价值。方法:选取本院自2016年9月至2017年3月收治的120例乙型肝炎后肝硬化的患者作为研究对象,将将全部患者分为2组,即代偿期组以及失代偿期组(各60例),并和同时期健康体检者定为对照组,观察和对比血清总胆汁酸指标。结果:对于乙型肝炎后肝硬化2个组患者,其测试所得到的血清总胆汁酸数据都高于正常对照者,并伴随着病情的逐渐进展,而继续增高;且乙型肝炎后肝硬化患者中,代偿期组合失代偿期组患者两组测试数据分别为(26.47±5.01)、(40.26±7.19)μmol/L,该两组数据对比亦显著的差异(P<0.05),具有统计学意义。结论:通过血清总胆汁酸可以清晰、准确的体现被测试者肝部受损的实际状况,对于乙型肝炎后肝硬化患者的治疗效果评价有极大临床价值,应当引起足够的重视。
Objective: To investigate and study the clinical value of serum total bile acid in the diagnosis of post-hepatitis B cirrhosis. Methods: A total of 120 patients with post-hepatitis B cirrhosis admitted from September 2016 to March 2017 in our hospital were enrolled. All patients were divided into 2 groups: decompensated group and decompensated group Group (each 60 cases), and the same period of health examination as a control group, observed and compared serum total bile acid. Results: The data of total serum bile acids in patients with posthepatitic cirrhosis in two groups were higher than that of the normal controls, accompanied by the gradual progress of the disease, and continued to increase; and posthepatitic cirrhosis The patients in the decompensated and decompensated groups had a significant difference (P <0.05) with the data of (26.47 ± 5.01) and (40.26 ± 7.19) μmol / L, respectively Statistical significance. Conclusion: The serum total bile acid can clearly and accurately reflect the actual condition of liver damage in the tested subjects. It has great clinical value in evaluating the therapeutic effect of patients with posthepatitic cirrhosis and should be given enough attention.