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本文报告应用巯甲丙脯酸在心梗后治疗心源性休克。3名年龄为55~68岁的病人虽然经静脉内注射多巴胺、多巴酚丁胺及Nitroprusal,但在心梗后12~24小时内仍处于心源性休克状态,分别接受静注巯甲丙脯酸。两名病人心梗部位前壁,一为下后壁。心输出量及肺毛细血管楔压用Swan—Ganz转换器监测,血压从挠动脉支记录。用药前收缩压为90mmHg或低于比值,肺毛细血管楔压大于25mmHg,心输出量低于2.1/分,尿排出量低于30ml/小时。巯甲丙脯酸开始口服量为1mg,在以后2~24小时剂量从6.25mg增至12.5mg,每天3次。在口服后10小时内,肺毛细血管楔压下降至16~22mmHg,心
This article reports the use of captopril in the treatment of cardiogenic shock after myocardial infarction. Three patients, aged 55-68, received intravenous injection of dopamine, dobutamine and Nitroprusal, but were still in cardiogenic shock within 12 to 24 hours after MI, receiving intravenous injection of mercaptopropril Prodigal acid. Two patients before the myocardial infarction site, one for the posterior wall. Cardiac output and pulmonary capillary wedge pressure were monitored using a Swan-Ganz transducer, and blood pressure was recorded from the flexible artery branch. Systolic blood pressure before treatment 90mmHg or less than the ratio of pulmonary capillary wedge pressure greater than 25mmHg, cardiac output is less than 2.1 / min, urinary output less than 30ml / hour. Captopril started at an oral dose of 1 mg and was increased from 6.25 mg to 12.5 mg 2 to 24 hours later 3 times a day. Within 10 hours after oral administration, pulmonary capillary wedge pressure dropped to 16 ~ 22mmHg, heart