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1名39岁女性躁狂症患者服用碳酸锂治疗,中午0.5 g和晚0.75 g及氯氮平中午12.5 mg和晚62.5 mg,持续10年余。约1年前,患者出现头晕、乏力、双腿发抖、双手震颤。经检查怀疑为锂中毒。检测示其血清锂浓度为2.4 mmol/L。停用碳酸锂,静脉滴注0.9%氯化钠注射液1 000 ml,1次/d,氯氮平继续服用。7 d后患者血清锂浓度降至0.33 mmol/L,其症状逐渐好转。
A 39-year-old female mania patient took lithium carbonate at 0.5 g at night and 0.75 g at night and 12.5 mg at night and 62.5 mg at night of clozapine for more than 10 years. About 1 year ago, the patient developed dizziness, weakness, trembling legs and trembling hands. After examination suspected lithium poisoning. Detection showed a serum lithium concentration of 2.4 mmol / L. Lithium carbonate was discontinued, and 0.9% sodium chloride injection (1 000 ml) was intravenously dripped once per day and clozapine continued to be taken. Serum lithium concentration decreased to 0.33 mmol / L after 7 days, and its symptoms gradually improved.