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目的观察糖脉康颗粒与甲钴胺联合治疗难治性糖尿病周围神经病变的疗效。方法60例难治性糖尿病周围神经病变分为对照组和治疗组,对照组30例,单用甲钴胺输注,1000μg/d,连用4周。治疗组在对照组的基础上,加用糖脉康颗粒口服,5g/次,3次/d,连用4周。结果治疗组有效率达90%,明显高于对照组50%(P<0.01);神经传导速度改善也明显优于对照组(P<0.01)。结论糖脉康颗粒联合甲钴胺应用可明显提高糖尿病周围神经病变的治疗效果。
Objective To observe the curative effect of Tangmaikang granule combined with mecobalamin in the treatment of refractory diabetic peripheral neuropathy. Methods Sixty patients with refractory diabetic peripheral neuropathy were divided into control group and treatment group. The control group consisted of 30 patients. Methylcobalamin alone was administered 1000 μg once daily for 4 weeks. On the basis of the control group, the treatment group was given Kangmaikang granule orally, 5g / time, 3 times / d for 4 weeks. Results The effective rate of the treatment group was 90%, which was significantly higher than that of the control group (P <0.01). The improvement of nerve conduction velocity was also significantly better than that of the control group (P <0.01). Conclusion Tangmaikang granule combined with mecobalamin can significantly improve the therapeutic effect of diabetic peripheral neuropathy.